The New Cathedral of Plasencia is a magnificent temple that stands out as one of the most ornate and opulent of all Extremadura.

The construction of this cathedral began in 1498 and was completed in 1578, although it faced periods of interruption. Later, during the 18th century, the work was resumed, but unfortunately it remained incomplete.

Its two Renaissance facades in Plateresque style are remarkable. The main façade, the work of Juan de Alava, was completed in 1558. It is composed of four sections and five streets that form an authentic altarpiece sculpted in stone. Although it lacks the planned statues, the work was possibly begun by Juan de Álava and completed by Gil de Hontañón, who added the upper body, the crests and the spires. The second façade, dated between 1538 and 1548, is traditionally attributed to Diego de Siloé.

Inside, the cathedral has three naves, all of equal height, an unusual feature for its time. A ribbed vault adorns the open transept.

The main altarpiece, in baroque style, dates from the 17th century. Created by Gregorio Fernández, it features polychrome wood carvings using the estofado technique. The paintings of Francisco Rizi stand out, including the canvases of the Annunciation and the Adoration of the Shepherds, as well as the works of Luis Fernandez and Mateo Gallardo: the Adoration of the Kings and the Circumcision, respectively.

The choir grille, a wrought iron work in Plateresque style, is attributed to Juan Bautista Celma. Completed in 1604 and gilded in 1763, it has the image of the Blessed Virgin at its peak. In its interior, it shelters the impressive choir stalls that previously were in the Old Cathedral. The organ, of plateresque style with touches of transition to baroque, was built by Casai Elezgaray.