The Basilica of the Holy Martyr Brothers, Vicente, Sabina and Cristeta, better known simply as the Basilica of San Vicente, is a Romanesque temple, the largest and most important in the city of Ávila after the Cathedral of El Salvador and one of the most outstanding works of this architectural style in the whole country. It was declared a National Monument in 1882.

It was expressly declared a World Heritage Site in 1985, as an individual element forming part of the Old City of Ávila and churches outside the walls.

In the year 306, during the persecution of Diocletian, and by order of the praetor Dacian, the siblings Vincent (from Avila), Sabina and Cristeta were martyred for refusing to sign a document in which they had to acknowledge having offered sacrifices to the Roman gods, as established in the fourth edict of the persecution, in 304. According to tradition, their bodies were deposited in a hollow in the rock, and the current basilica was later built on this site (the rock is the one that can be seen in the right-hand chapel of the crypt).

Legend has it that it was the Jew responsible for their death who, repentant, decided to build a temple to bury them, a passage that appears in a relief on the cenotaph.

The material used for the construction is 'caleña stone', a sandstone of yellowish and orangey tones with reddish veins due to its iron oxide content, from the quarries in the nearby village of La Colilla. In some areas, such as the main altar and the south apse, a variety particularly rich in reddish hues was used, known as "bleeding sandstone".