The 1852 stone-milled San Antonio flour mill in Medina de Rioseco stands at the Canal de Castilla basin's first waterfall. On February 28, 2008, it became a Monument Asset of Cultural Importance.

The flour business in Valladolid was enhanced in the 19th century by the Castile Canal (1849) and the railway (1864).

In 1912, it was reformed to include contemporary cleaning and milling equipment. Flour shipments to warring nations increased in 1914 due to Spain's neutrality.

The current production method was reformed in 1944. The working schematic produced by Swiss flour installation specialist Daverio for Mr. Antonio de Hoyos "to automatically mill 17,000 kilogrammes of soft wheat in 24 hours" is from the same year.

The Municipal Council of Medina de Rioseco bought it a few years after it stopped operations.

The factory's major appeal is the 1944 machinery that hasn't changed much.

As mentioned, the production project and installation were completed in 1944 by the Swiss firm Daverio, whose trademark appears on most of the machines. The rest of the machinery has trademarks from Robinson, Buhler, Morros, Gombar, Henri Simon, and Pérez y Montané, and Siemens motors and electrical appliances.